Research Fellowship

我研究线粒体疾病，这是一种遗传性新陈代谢障碍，阻止食物能量转化为我们细胞所需的化学能量。我们的重点是通过大规模平行测序、系统生物学和实验研究等方法了解这些疾病的遗传基础，以及(Ii)通过研究患者和动物模型的细胞系来了解疾病的详细机制。我们的目标是开发更好的诊断、治疗和预防方法。

I work on mitochondrial diseases, which are inherited disorders of metabolism that block conversion of food energy into chemical energy needed by our cells. We focus on understanding (i) the genetic basis of these disorders using approaches such as massively parallel sequencing, systems biology and experimental studies, and (ii) the detailed mechanisms of disease by studying cell lines from patients and animal models. We aim to develop better methods for diagnosis, treatment and prevention.