Genetic history of human populations

我们提出了一个长期的研究计划，旨在利用来自x染色体片段的遗传信息来表征当今人类种群的遗传结构。我们的同事们对mtDNA和y染色体进行了类似的研究，已经在世界各地的许多实验室收集了20多年的数据。我们希望通过使用x连锁变异提供核基因组的新信息来补充这一全球努力。到目前为止，这项工作已经提供了非常有趣的结果，补充了以前从其他遗传系统（如mtDNA和y染色体）获得的发现，最重要的是，带来了定量的新数据，导致了对人类种群历史的新假设和新观点。

We present a long-term research program that aims at characterizing the genetic structure of present-day human populations using genetic information from segments of the X-chromosome. Our colleagues following a similar line of work with mtDNA and Y-chromosome have been collecting data for more than two decades in numerous laboratories all over the world. We want to complement this global effort by providing new information from the nuclear genome using X-linked variation. So far this work has provided unusually interesting results, complementing previous findings from other genetic systems such as mtDNA and the Y-chromosome, and most importantly bringing quantitatively new data leading to new hypotheses and views of human population history.