Shaken baby syndrome: characterization of a model and evaluation of novel pharmacological therapies

摇晃婴儿综合征是2岁以下婴儿的一种创伤性脑损伤。它导致10- 40%的病例死亡，幸存者出现神经系统问题。没有治疗方法，主要是因为没有一个很好的表征模型的综合征，复制人类的情况。这项研究将充分表征我们新开发的摇晃婴儿综合征模型，并检查针对脑肿胀的新型干预策略的有效性。

Shaken baby syndrome is a form of traumatic brain injury in infants less than 2 years of age. It results in death in 10-40 % of cases, and neurological problems in survivors. No treatment exists largely because there is no well characterized model of the syndrome that replicates the human situation. This study will fully characterize our newly developed model of shaken baby syndrome and examine the effectiveness of a novel interventional strategy targeting brain swelling.