课题基金 / 基金详情

Simvastatin prevents dopaminergic neuronal injury in experimental PD models via activation of NF-kB and MMP 9 and 3

Simvastatin prevents dopaminergic neuronal injury in experimental PD models via activation of NF-kB and MMP 9 and 3
辛伐他汀通过激活 NF-kB 和 MMP 9 和 3 预防实验性 PD 模型中的多巴胺能神经元损伤
批准号：
nhmrc : 514640
负责人：
Qing Wang
金额：
$5.86万
依托单位：
University of Wollongong
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2008
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2008-01-01 至 2009-12-31
来源：
https://researchdata.edu.au/simvastatin-prevents-dopaminergic-9-3/115673
关键词：
Simvastatinpreventsdopaminergicneuronalinjury

项目摘要

项目成果

Qing Wang的其他基金

相似基金

相关文献

中文摘要
翻译
越来越多的证据表明，神经炎症可能是帕金森病（PD）多巴胺神经元死亡的原因。本研究的目的是提供帕金森病炎症反应的系统图像，并探讨辛伐他汀对帕金森病的抗炎作用机制。我们期望这些结果可以为辛伐他汀通过不同给药方法治疗PD提供一种治疗策略，并为辛伐他汀的抗炎作用提供新的信息。
英文摘要
Increasing evidence shows that neuroinflammation may account for dopamine neuron death in Parkinson’s disease (PD). This work aims to provide systematic picture of inflammatory response in PD, and explore anti-inflammatory mechanisms of simvastatin on the progression of PD. We expect that the results may provide a therapeutic strategy using simvastatin via different methods of administration in treating PD, and provide new information about the anti-inflammatory roles of simvastatin.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Advancing Academic Success and Career Development for Talented, Low-Income Computer Science, Mathematics, and Engineering Majors
  • 批准号：
    2130267
  • 项目类别：
    Standard Grant
  • 资助金额：
    $150.0万
  • 财政年份：
    2021
  • 负责人：
    Qing Wang
  • 依托单位：
    Shepherd University
Ferroelectric Gradient Microfoams as High-Performance Self-Powered Flexible Pressure Sensors
SusChEM: Nonflammable, Highly Conductive Ionic Liquid based Organic-Inorganic Hybrid Electrolytes for Lithium Batteries
Rational Design and Manufacturing of Ceramic-Polymer Composites for Solid State Cooling using the Electrocaloric Effect
海外基金