Strategies to reduce the burden of gastroenteritis in Aboriginal children.

轮状病毒是导致儿童严重胃肠炎的主要原因。尽管早期的承诺，针对轮状病毒的疫苗似乎在低资源环境中以及澳大利亚土著儿童中效果较差。本研究旨在评估额外剂量的轮状病毒疫苗（RV1）是否会提高轮状病毒疫苗在原住民儿童中的有效性，并导致在生命的前三年减少入院和诊所就诊。

Rotavirus is the leading cause of severe gastroenteritis in children. Despite early promise, vaccines which target rotavirus seem to be less effective in low-resource settings and also amongst Australian Indigenous children. This study seeks to assess whether an extra dose of rotavirus vaccine (RV1) will improve the effectiveness of rotavirus vaccine in Aboriginal children and result in decreased admissions and clinic visits in the first three years of life.