Tako-Tsubo Cardiomyopathy: pathogenesis and natural history

Tako-Tsubo心肌病（TTC）：心碎综合征是急性心力衰竭的一种鲜为人知的原因，通常发生在暴露于严重情绪压力的绝经后妇女中。我们将探讨TTC的最佳诊断方法，确定其分子原因以及短期和长期对心脏和血管功能的影响。这项研究可能会改善TTC的检测和管理，并可能指出预防TTC的方法。

Tako-Tsubo cardiomyopathy (TTC): broken heart syndrome is a poorly-understood cause of acute heart failure which usually occurs in post-menopausal women exposed to severe emotional stress. We will investigate the best way to diagnose TTC, identify its molecular causes and impact in the short and long-term on cardiac and blood vessel function. This research potentially should improve the detection and management of TTC, and may point to ways for its prevention.