Targeted nanoparticle delivery of agents to the placenta to treat preeclampsia

先兆子痫是妊娠最严重的并发症之一，约占所有妊娠的3%-8%。遗憾的是，目前还没有治疗方法。我们已经开发了一种新的技术，只对胎盘进行治疗，使母亲和婴儿免受副作用。我们将在实验室的小鼠模型和人类组织样本中测试这项技术是否可以治疗先兆子痫的来源-胎盘。这项工作可能会为其他妊娠并发症提供新的治疗方法。

Preeclampsia, one of the most serious complications of pregnancy, affects around 3-8% of all pregnancies. Sadly, there is no treatment. We have developed a new technique to deliver treatments only to the placenta, sparing the mother and baby from side effects. We will test whether this technique can treat the source of preeclampsia, the placenta, in mouse models and human tissue samples in the laboratory. This work may offer possibilities of new treatments to other pregnancy complications.