Targeting the Cytoskeleton in Cancer
Targeting the Cytoskeleton in Cancer
批准号:
nhmrc : 510140
负责人:
Prof Maria Kavallaris
金额:
$34.65万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31
中文摘要
癌细胞的特征之一是它们能够以不受控制的方式分裂和繁殖。构成细胞骨架(细胞骨架)的特定蛋白质在细胞分裂过程中起着重要作用,因此成为抗癌治疗的极其重要的靶点。我们的研究是寻找最佳的靶向细胞分裂蛋白的方法,这样我们就可以使耐药的癌细胞对化疗敏感。
英文摘要
One of the hallmarks of cancer cells is their ability to divide and multiply in an uncontrolled manner. Specific proteins that make up the skeleton of cells (cytoskeleton) play an important part in the cell division process and as such make extremely important targets for anticancer therapy. Our research is developing ways to best target cell division proteins so that we can make drug resistant cancer cells sensitive to chemotherapy.
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会议论文
Precision nanomedicine-based cancer therapeutics
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批准号:nhmrc : GNT1119152
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项目类别:Research Fellowships
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资助金额:$76.38万
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财政年份:2017
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负责人:Prof Maria Kavallaris
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依托单位:
Precision nanomedicine-based cancer therapeutics
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批准号:nhmrc : 1119152
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项目类别:Research Fellowships
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资助金额:$52.22万
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财政年份:2017
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负责人:Prof Maria Kavallaris
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依托单位:
Regulation & targeting of the cancer cytoskeleton
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批准号:nhmrc : 1058299
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项目类别:Research Fellowships
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资助金额:$41.72万
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财政年份:2014
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负责人:Prof Maria Kavallaris
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依托单位:
Structural domains of beta-tubulin and their role in microtubule dynamics and transport
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批准号:DP140103290
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项目类别:Discovery Projects
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资助金额:$23.97万
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财政年份:2014
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负责人:Prof Maria Kavallaris
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 568611
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项目类别:NHMRC Research Fellowships
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资助金额:$38.72万
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财政年份:2009
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负责人:Prof Maria Kavallaris
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依托单位:
Targeted development of dual action antitumour and antiangiogenic agents using differential and functional proteomics
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批准号:LP0775181
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项目类别:Linkage Projects
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资助金额:$16.14万
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财政年份:2007
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负责人:Prof Maria Kavallaris
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依托单位:
Molecular and Cellular Determinants of Tubulin-targeted Drug Action
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批准号:nhmrc : 350878
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项目类别:NHMRC Project Grants
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资助金额:$32.31万
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财政年份:2005
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负责人:Prof Maria Kavallaris
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依托单位:
Molecular determinants of cancer therapeutic drug response
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批准号:nhmrc : 300580
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项目类别:Career Development Fellowships
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资助金额:$29.64万
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财政年份:2004
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负责人:Prof Maria Kavallaris
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依托单位:
The role of microtubule composition in the efficacy of antimicrotubule agents in paediatric malignancy
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批准号:nhmrc : 113837
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项目类别:NHMRC Project Grants
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资助金额:$11.56万
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财政年份:2000
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负责人:Prof Maria Kavallaris
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依托单位:
国内基金
海外基金
Piezo1/Cytoskeleton介导的YAP核易位在4D仿生骨膜修复骨缺损中的作用及机制研究
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批准号:--
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项目类别:青年科学基金项目
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资助金额:30万元
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批准年份:2022
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负责人:游东奇
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依托单位: