Therapeutic Profiling of Atherosclerosis: Identifying and Testing Specific Targets in Plaque Instability

心脏病是最常见的单一死因。它通常是由动脉粥样硬化斑块破裂和随后的心脏供血动脉阻塞引起的。由于缺乏动物模型，预防心脏病发作的进展受到阻碍，我们最近开发了动物模型，并计划使用动物模型来确定导致心脏病发作的因素。我们还描述了有可能预防心脏病发作的新药和纳米颗粒。

Heart attacks are the most frequent single cause of death. It is typically caused by rupture of atherosclerotic plaques and subsequent blockage of the arteries that supply the heart with blood. Advances towards the prevention of heart attacks have been hampered by the lack of an animal model, which we have recently developed and are planning to use to identify factors responsible for heart attacks. We also describe new drugs and nanoparticles that have the potential to prevent heart attacks.