Traumatic Brain Injury, Post Traumatic Stress Disorder and the Risk of Neurodegenerative Disease: a study of tau and beta-amyloid accumulation, brain structure and function several decades after injury.

该研究旨在更好地了解创伤性脑损伤（TBI）、创伤后应激障碍（PTSD）与痴呆，特别是阿尔茨海默病（AD）和慢性创伤性脑病（CTE）之间的关系。这项研究将对退役的AFL球员、道路创伤受害者和越南退伍军人进行高级成像，使用PET脑部扫描来检测AD和CTE典型的异常大脑沉积物，并评估脑损伤和创伤后应激障碍后来发展为这些疾病的风险。

The study aims to better understand the association between traumatic brain injury (TBI), post traumatic stress disorder (PTSD) and dementia, specifically Alzheimer’s disease (AD) and chronic traumatic encephalopathy (CTE). The study will examine retired AFL players, road trauma victims and Vietnam veterans with advanced imaging using PET brain scans for the abnormal brain deposits typical of AD and CTE and assess the risk of later developing these diseases from head injury and PTSD.