课题基金 / 基金详情

Tubulovillous Adenomas in Colorectal Tumorigenesis

Tubulovillous Adenomas in Colorectal Tumorigenesis
结直肠肿瘤发生中的管状绒毛状腺瘤
批准号:
nhmrc : 552473
负责人:
A/Pr Vicki Whitehall
金额:
$19.74万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31

项目摘要

项目成果

A/Pr Vicki Whitehall的其他基金

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中文摘要
翻译
肠癌是当今影响澳大利亚人的第二种最常见的癌症,所有患者中有一半无法存活。肠癌是由称为息肉的小肿瘤发展而来的。在这个项目中,我们的目标是研究在一种特别侵袭性的称为管状绒毛状腺瘤的肠息肉中发现的基因变化。更好地了解这些基因变化将有助于未来分子检测的发展,以早期发现和治疗癌症的选择。
英文摘要
Bowel cancer is the second most common cancer affecting Australians today, and half of all patients will not survive their disease. Bowel cancer grows from small growths called polyps. In this project, we aim to investigate changes in genes found in a particularly aggressive type of bowel polyp called a tubulovillous adenoma. A better understanding of these gene changes will aid the future development of molecular tests for early detection and therapeutic options for the treatment of cancer.
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会议论文
Wnt and MAPK Signalling in the Determination of Colorectal Neoplasia Pathway
KRAS- and BRAF-Mediated Methylation Signatures in Colorectal Cancers and Polyps
The CpG Island Methylator Phenotype in Colorectal Cancer - Pathways and Precursors
  • 批准号:
    nhmrc : 442965
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $34.49万
  • 财政年份:
    2007
  • 负责人:
    A/Pr Vicki Whitehall
  • 依托单位:
Identification of Downstream Effectors of the hMSH2/hMLH1 Damage Sensing Apparatus
  • 批准号:
    nhmrc : 241965
  • 项目类别:
    Early Career Fellowships
  • 资助金额:
    $25.67万
  • 财政年份:
    2003
  • 负责人:
    A/Pr Vicki Whitehall
  • 依托单位:
海外基金