Unravelling the behavioural and brain mechanisms of compulsive disorders, and new ways to treat them

强迫症，如强迫症和物质使用障碍，是慢性的，使人衰弱的，给个人和社会带来巨大的代价。这些疾病共同影响超过10%的人口。此外，这些人中有40-60%对目前的治疗有抵抗力。目前的项目旨在改善临床前研究，使我们了解这些疾病的行为和大脑机制以及如何治疗它们。

Disorders of compulsion, such as obsessive-compulsive disorder and substance use disorder, are chronic, debilitating, and present a significant cost to the individual and to society. Together, these disorders affect more than 10% of the population. Moreover, 40-60% of these individuals are resistant to current treatment. The current project is aimed at improving the preclinical research underlying our understanding the behavioural and brain mechanisms of such disorders and how to treat them.