Using Metagenomics to Determine the Causative Agent(s) of Tick-Borne Disease in Australia

蜱传疾病已成为澳大利亚的一个热点和有争议的公共卫生问题。我们将采用宏基因组学中最先进的技术来确定澳大利亚蜱虫中传播的微生物物种（细菌，病毒和真核生物）以及这些或不同的微生物是否也存在于被诊断患有蜱传疾病的人类中。所产生的数据将提供有关蜱传疾病是否具有微生物原因的关键信息，如果是，则涉及微生物。

Tick-borne disease has emerged as a topical and controversial public health problem in Australia. We will employ state-of-the-art techniques in metagenomics to determine what microbial species (bacteria, viruses and eukaryotes) circulate in Australian ticks and whether these or different microbes are also present in humans diagnosed with tick-borne disease. The data generated will provide key information on whether tick-borne disease has a microbiological cause and, if so, the microbes involved.