Vaccine to prevent Influenza Virus and Bacterial super-infection.
Vaccine to prevent Influenza Virus and Bacterial super-infection.
批准号:
nhmrc : 2000435
负责人:
金额:
$70.77万
依托单位国家:
澳大利亚
项目类别:
Ideas Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2024-12-31
中文摘要
流感病毒有能力使受感染的宿主倾向于继发性细菌并发症。并发或继发细菌感染(称为超级感染)的病毒感染的死亡率通常高于单独的病毒或细菌。我们将开发一种新的多病原体候选疫苗,用于对抗主要的上呼吸道病原体-甲型流感和化脓性链球菌,以预防双重感染。
英文摘要
Influenza viruses have the ability to pre-dispose infected hosts toward secondary bacterial complications. The mortality of viral infections that are complicated by a concurrent, or subsequent, bacterial infection (known as a super-infection), is often greater than that of either the virus or the bacteria alone. We will develop a novel multi-pathogen vaccine candidate against the major upper respiratory tract pathogens - Influenza A and Streptococcus pyogenes to prevent super-infections.
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