Validation of non-invasive finite element method based localization of seizure onset zone in epilepsy using EEG-MEG

大脑中的癫痫发作通常是局灶性的。如果抗癫痫药物无效，可以植入脑深部刺激器，在癫痫发作时中止发作，或者切除癫痫组织。该项目旨在利用大脑电磁场的真实计算机模型，从癫痫样大脑活动的非侵入性脑电-脑磁图记录中定位癫痫组织。更准确地了解位置将改善脑深部刺激和切除手术的结果。

Epileptic seizures in the brain are often focal. If anti-epileptic drugs are ineffective, a deep brain stimulator may be implanted to abort seizures at their onset or the seizure tissue may be removed. This project aims to locate the seizure tissue from non-invasive EEG-MEG recordings of seizure-like brain activity using a realistic computer model of the electromagnetic fields in the brain. Knowing the location more exactly will improve the outcomes of deep brain stimulation and removal surgery.