Vasomotor ganglionic transmission: the preganglionic peptide and the second gear
Vasomotor ganglionic transmission: the preganglionic peptide and the second gear
批准号:
nhmrc : 1010907
负责人:
A/Pr Colin Anderson
金额:
$30.13万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
血压取决于从中枢神经系统传递到血管的神经信号。在这条通路的中间是一个中继站——交感神经节细胞。通过这个中继站的传输最近被证明不仅有一个固定的组件,而且还有一个可变的组件-“第二齿轮”。该项目测试了三种可能的候选肽分子(一个在神经中,两个在血液中)是否以及如何控制这种“第二齿轮”,从而调节血压。
英文摘要
Blood pressure depends on nerve signals that travel from the central nervous system to blood vessels. In the middle of this pathway is a relay station - the sympathetic ganglion cell. Transmission through this relay station has recently been shown to have not only a fixed but also a variable component - the 'second gear'. The project tests if and how three likely candidate peptide molecules, one in the nerves, two in the bloodstream, control this 'second gear' and hence regulate blood pressure.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Differentiation and fate in the developing sympathetic ganglia
-
批准号:nhmrc : 1063822
-
项目类别:Project Grants
-
资助金额:$23.59万
-
财政年份:2014
-
负责人:A/Pr Colin Anderson
-
依托单位:
Differentiation and fate in the developing sympathetic ganglia
-
批准号:nhmrc : GNT1063822
-
项目类别:Project Grants
-
资助金额:$22.81万
-
财政年份:2014
-
负责人:A/Pr Colin Anderson
-
依托单位:
Control of Sympathetic Nerves that Talk to the Immune System
-
批准号:nhmrc : 628655
-
项目类别:NHMRC Project Grants
-
资助金额:$25.74万
-
财政年份:2010
-
负责人:A/Pr Colin Anderson
-
依托单位:
The development of glial cells in the sympathetic nervous system
-
批准号:nhmrc : 509000
-
项目类别:NHMRC Project Grants
-
资助金额:$24.81万
-
财政年份:2008
-
负责人:A/Pr Colin Anderson
-
依托单位:
Determination of sympathetic preganglionic neuronal phenotype
-
批准号:nhmrc : 145634
-
项目类别:NHMRC Project Grants
-
资助金额:$16.11万
-
财政年份:2001
-
负责人:A/Pr Colin Anderson
-
依托单位:
The role of gap functions in the development of the phenotype of autonomic neurons
-
批准号:nhmrc : 980652
-
项目类别:NHMRC Project Grants
-
资助金额:$12.79万
-
财政年份:1998
-
负责人:A/Pr Colin Anderson
-
依托单位:
海外基金