Pioneering alpine epigenomics to discover adaptive genetic elements

本土植物的遗传密码尚未被探索，以寻找促进对气候变化的适应能力的DNA元素。由于表观基因组学的最新进展允许快速识别，这些元素现在已经成熟。这项提议旨在发现蜡制蓝铃花中与热有关的元素，这种植物栖息在澳大利亚脆弱的高地。预期成果包括对本土植物基因调控机制的新见解;产生遗传保护资源，并促进对澳大利亚植物群的进一步分子研究。这将通过揭示本土植物的基因组调控，从而提高预测气候变化影响的能力，带来重大益处。

The genetic code of native plants are yet to be explored for DNA elements that promote resilience to climate change. These elements are now ripe for discovery due to recent advances in epigenomics allowing for rapid identification. This proposal aims to discover heat-associated elements in waxy bluebells, which inhabit Australia’s vulnerable high country. Expected outcomes include new insights on gene regulatory mechanisms in native plants; the generation of resources for genetic conservation, and catalysing further molecular research into Australian flora. This should provide significant benefits by revealing genome regulation in native plants, thereby improving the ability to predict the impacts of climate change.