Isolation and characterization of cell signalling systems that activate or suppress apoptosis in pathogenic and symbiotic fungal:plant interactions.

病原真菌和共生真菌中激活或抑制细胞凋亡的细胞信号系统的分离和表征：植物相互作用。细胞程序性死亡(PCD)在植物病害中的关键作用日益明显。该项目将测试以下假设：丛枝菌根在植物根中的成功定殖需要植物上调PCD的抑制剂；植物对坏死性真菌病原体的敏感性需要触发PCD；抗药性是PCD抑制剂激活的结果。这一国际项目将对控制植物病害和共生具有重要的生物学和经济意义，将在国际专业领域培训早期职业研究人员，并将加强美国和澳大利亚研究小组之间的合作。

Isolation and characterization of cell signalling systems that activate or suppress apoptosis in pathogenic and symbiotic fungal:plant interactions. The key roles of programmed cell death (PCD) in plant disease are becoming apparent. This project will test the hypotheses that successful colonisation by arbuscular mycorrhizae in plant roots requires the plant to up-regulate inhibitors of PCD; that susceptibility in plants to necrotrophic fungal pathogens requires triggering of PCD; and that resistance is the result of activation of inhibitors of PCD. This international project will have important implications biologically and economically for control of plant disease and symbiosis, will train early career researchers in an area of international expertise and will strengthen collaboration between the US and Australian research group