ON-LINE PRECONCENTRATION IN CAPILLARY ELECTROSEPARATIONS USING SEGMENTED CAPILLARIES

分段毛细管电分离中的在线预富集本计画旨在发展毛细管电泳及毛细管电色谱中痕量分析物的线上富集新方法。所使用的毛细管将包括预浓缩区和分离区，研究主要集中在预浓缩区的化学性质上。将使用由壁涂层和固体固定相形成的预浓缩器。该项目将产生新的、高灵敏度的无机离子、低分子量酸和碱以及蛋白质和肽的分析方法。这些方法将应用于广泛的重要领域，包括环境分析和生物技术。

ON-LINE PRECONCENTRATION IN CAPILLARY ELECTROSEPARATIONS USING SEGMENTED CAPILLARIES. This project aims to develop new on-line methods for trace enrichment of analytes in capillary electrophoresis and capillary electrochromatography. The capillaries to be used will comprise a preconcentration zone and a separation zone with the research focusing predominantly on the chemistry of the preconcentration zone. Preconcentrators formed from wall-coatings and solid stationary phases will be used. The project will result in new, highly sensitive analytical methods for inorganic ions, low molecular weight acids and bases, and proteins and peptides. These methods will have application in a wide range of important areas including environmental analysis and biotechnology.