Pretreatment, hydrolysis and fermentation of lignocellulosic material

提出的研究的短期目标是优化木质纤维素废料或其他低成本木质纤维素材料的水解和发酵。我们的重点主要是预处理和发酵抑制混合糖底物。最终，目标是逐步改进单元操作，使整个过程的经济效益变得可行。在这个总体目标内，我们有若干具体目标，即：(1)提高我们对木质素作为酶解抑制剂的作用的理解；(2)通过延长反应条件和使用催化剂，进一步发展氧脱木质素作为酶解的预处理；(3)扩大所评估的底物，包括回收纤维和混合城市木质纤维素；(4)开发水解产物可以容易地和定量发酵成乙醇的条件。

The short-term objective of the proposed research is to optimize the hydrolysis and fermentation of lignocellulosic wastes or other low cost lignocellulosic materials. Our focus is primarily on pretreatment and on fermentation of inhibitory mixed sugar substrates. Ultimately, the goal is to incrementally improve the unit operations such that the overall economics of the process become viable. Within this overall objective, we have a number of specific objectives, namely to: (1) Improve our understanding of the role of lignin as an inhibitor of enzymatic hydrolysis, (2) to further develop oxygen delignification as a pretreatment for enzymatic hydrolysis, by extending the reaction conditions and through the use of catalysts, (3) to extend substrate evaluated to include recycled fibre and mixed urban lignocellulosics, (4) to develop conditions whereby hydrolysates can be readily and quantitatively fermented to ethanol.