Modelling rumen function and subsquent nutrient utilisation

拟议的计划是我对瘤胃功能建模和随后的营养利用研究的延续;这是一项多年来一直积极开展的工作计划。六个新的发展计划，其中三个涉及消化和三个后吸收代谢：（一）扩大瘤胃脂肪酸子模型;（二）原生动物动力学的改进描述;（三）扩大物理描述的瘤胃和后肠;和氮代谢模型（四）肠壁;（五）肝脏;（六）乳腺。统计荟萃分析和动态建模将用于追求每个目标。在完成这些发展之后，将以方便用户的决策支助系统的形式制作一个综合模型。这将使反刍家畜的饲养策略更有效，并设计减少甲烷排放和氮污染的选择。

The proposed programme is a continuation of my research into modelling rumen function and subsequent nutrient utilisation; a programme of work that has been actively pursued over several years. Six new developments are planned, three of which pertain to digestion and three to post-absorptive metabolism: (i) an extended rumen fatty acid sub-model; (ii) an improved description of protozoal dynamics; (iii) an expanded physical description of the rumen and hindgut; and models of nitrogen metabolism in (iv) gut wall; (v) liver; and (vi) mammary gland. Statistical meta-analysis and dynamic modelling will be used in pursuance of each objective. Having accomplished these developments, an integrated model will be produced in the form of a user-friendly decision support system. This will allow more efficient feeding strategies for ruminant livestock and options for mitigating methane emissions and nitrogen pollution to be devised.