课题基金 / 基金详情

Investigation of the roles of schizophrenia susceptibility genes DISC1 and DTNBP1 in cognition, learning, memory, and rodent models of psychiatric disease

Investigation of the roles of schizophrenia susceptibility genes DISC1 and DTNBP1 in cognition, learning, memory, and rodent models of psychiatric disease
精神分裂症易感基因DISC1和DTNBP1在精神疾病认知、学习、记忆和啮齿动物模型中的作用研究
批准号：
184611
负责人：
Feldcamp Laura A
金额：
$7.65万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-10-01 至 2011-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184611&lang=en
关键词：
Disc1 Dysbindin1 Immunohistochemistry In-Situ Hybridization Learning And Memory Lentiviral-Mediated Upregulation Of Mrna/Protein Prepulse Inhibition Real-Time Rt-Pcr Schizophrenia Model Sirna Downregulation Of Mrna/Protein

项目摘要

项目成果

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中文摘要
翻译
我们项目的目标是确定两个候选精神分裂症易感基因DTNBP1 （dysstobrevin -binding protein 1/Dysbindin1）和DISC1 （disruptedin -schizophrenia 1）在学习、记忆、认知和其他障碍中的作用
英文摘要
The goal of our project is to determine the role of two candidate schizophrenia susceptibility genes, DTNBP1 (Dystobrevin-binding protein 1/Dysbindin1) and DISC1 (Disrupted-in-schizophrenia 1), in the disruption of learning, memory, cognition, and other m
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