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Mitochondrial delivery of DNA-alkylating anticancer agents

Mitochondrial delivery of DNA-alkylating anticancer agents
DNA 烷基化抗癌药物的线粒体递送
批准号:
238344
负责人:
Kelley Shana O
金额:
$37.49万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2015-09-01

项目摘要

项目成果

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中文摘要
翻译
我们正在开发一种化合物,以逃避癌细胞用来推翻抗癌治疗效果的耐药机制。通过将药物输送到细胞内的一个独特位置,治疗分子被隐藏起来,不被灭活剂激活,并使其
英文摘要
We are developing compounds that evade the resistance mechanisms that cancer cells use to override the effects of anticancer therapies. By delivering the drug to a unique site within the cell, therapeutic molecules are hidden from deactivators and made m
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