MODERN BIOBUBBLE UNITS TO SUPPORT BASIC RESEARCH USING ANIMAL MODELS
MODERN BIOBUBBLE UNITS TO SUPPORT BASIC RESEARCH USING ANIMAL MODELS
批准号:
421965-2012
负责人:
Ma, David
金额:
$8.69万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31
中文摘要
我们的研究团队从事生理学和新陈代谢方面的基础研究。动物模型是基础科学研究的重要工具。特别是,越来越多的转基因小鼠或独特培育的大鼠模型已经变得容易获得。如果没有这些模型,我们对生理学和新陈代谢的基本理解就不可能取得许多重大进展。我们系通过招聘7名新教师和现有研究项目的增长,经历了巨大的增长。在满足当前需求和继续扩大研究活动方面存在重大障碍。我们需要一个生物泡沫单元来满足我们的迫切需求,这一迫切需求不仅要支持现有和新聘教员的需求,而且还要推动新领域的研究。这些单元允许安置专门的研究动物(小鼠、大鼠和兔子模型),用于癌症、免疫学和肠道研究,需要高水平的环境控制。目前,我们的设施已达到最大产能。通过使用尖端的生物泡沫装置,可以很容易地实现扩张。这些单元还具有很高的成本效益,其成本仅为传统和昂贵的实体房间的三分之一,这些房间需要与建筑基础设施相连的专门湿度和空气交换系统。收购拟议的生物泡沫室将满足对15个研究实验室及其100多名受训人员的重大需求。
英文摘要
Our team of investigators conduct basic research in physiology and metabolism. Animal models are important tools in basic science research. In particular, there are growing numbers of genetically altered mice or uniquely bred rat models that have become readily available. Without these models many significant advances in our fundamental understanding of physiology and metabolism would not be possible. Our department has experienced tremendous growth through the hiring of 7 new faculty hires and also growth of existing research programs. A significant barrier exists to meeting current needs and continued expansion of research activities. We are in need of a biobubble units to meet our urgent needs to address a critical need to not only support the needs of existing and new faculty hires, but also to advance research into new areas. These units permit the housing of specialized research animals (mouse, rat and rabbit models) used in cancer, immunology and gut research, requiring a high level of environmental containment. Currently, we are at maximum capacity in our facility. Expansion can be readily achieved through the use of cutting edge biobubble units. These units are also highly cost effective and at a third of the cost of traditional and expensive brick and mortar rooms that require specialized humidity and air exchange systems linked to the building infrastructure. The acquisition of a the proposed biobubble units will address a significant need for 15 researcher laboratories and upwards of 100 of their trainees.
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依托单位:
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Structure, function and mechanisms by which fatty acids modulate cellular signalling
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Food for Health Workshop
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依托单位:
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Modern cage washer to support basic research using rodent models
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依托单位:
Cellular and molecular mechanisms by which dietary fatty acids inhibit cancer
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项目类别:Discovery Grants Program - Individual
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