Pretreatment, hydrolysis and fermentation of lignocellulosic material

所提出的研究的短期目标是优化木质纤维素废物或其他低成本木质纤维素材料的水解和发酵。 我们的重点主要是预处理和发酵的抑制性混合糖底物。 最终，目标是逐步改善单元操作，使得该方法的总体经济性变得可行。在这一总体目标范围内，我们有一些具体目标，即：（1）提高我们对木质素作为酶水解抑制剂的作用的理解，（2）通过扩展反应条件和通过使用催化剂，进一步开发氧脱木质素作为酶水解的预处理，（3）扩展评估的底物以包括回收纤维和混合城市木质纤维素，（4）开发使水解产物可以容易地和定量地发酵成乙醇的条件。

The short-term objective of the proposed research is to optimize the hydrolysis and fermentation of lignocellulosic wastes or other low cost lignocellulosic materials. Our focus is primarily on pretreatment and on fermentation of inhibitory mixed sugar substrates. Ultimately, the goal is to incrementally improve the unit operations such that the overall economics of the process become viable. Within this overall objective, we have a number of specific objectives, namely to: (1) Improve our understanding of the role of lignin as an inhibitor of enzymatic hydrolysis, (2) to further develop oxygen delignification as a pretreatment for enzymatic hydrolysis, by extending the reaction conditions and through the use of catalysts, (3) to extend substrate evaluated to include recycled fibre and mixed urban lignocellulosics, (4) to develop conditions whereby hydrolysates can be readily and quantitatively fermented to ethanol.