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Identification and characterization of Protein Phosphatase 1 interactors by affinity-purification and quantitative mass spectrometry using differential metabolic labeling

Identification and characterization of Protein Phosphatase 1 interactors by affinity-purification and quantitative mass spectrometry using differential metabolic labeling
使用差异代谢标记通过亲和纯化和定量质谱法鉴定和表征蛋白磷酸酶 1 相互作用物
批准号：
253397
负责人：
Freele Emily A
金额：
$1.27万
依托单位：
University of Ottawa
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-02-01 至 2013-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253397&lang=en
关键词：
Affinity Purification Cancer Prevention Cloning Fluorescence Microscopy Immunohistochemistry Key Regulator Of Many Essential Pathways Mutagenesis Phosphatase Assay Quantitative Mass Spectrometry Western Blot Analysis

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中文摘要
翻译
蛋白质PP1在细胞的许多基本途径中都很重要。PP1功能的破坏可导致癌症和糖尿病等疾病的发展。我们的项目包括确定PP1调节哪些蛋白质。这项研究将有助于
英文摘要
The protein PP1 is important in many essential pathways in the cell. Disruptions in PP1 function can lead to the development of diseases such as cancer and diabetes. Our project involves determining which proteins PP1 is regulating. This research will aid
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