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A Systems Genetics Approach using induced pluripotent stem cells to elucidate novel therapeutic treatments and causes of Lymphangioleiomyomatosis (LAM) disease

A Systems Genetics Approach using induced pluripotent stem cells to elucidate novel therapeutic treatments and causes of Lymphangioleiomyomatosis (LAM) disease
使用诱导多能干细胞的系统遗传学方法来阐明淋巴管平滑肌瘤病 (LAM) 疾病的新治疗方法和病因
批准号：
253091
负责人：
Agnihotri Sameer
金额：
$9.83万
依托单位：
Ottawa Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-02-01 至 2015-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253091&lang=en
关键词：
Cancer Research Epigenetics Induced Pluripotent Stem Cells Lymphangioleiomyomatosis (Lam) Mouse Models Small Molecule Inhibitor Screen Systems Biology Systems Genetics

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中文摘要
翻译
淋巴管肌瘤病(LAM)是一种罕见的破坏性肺部疾病，主要影响年轻女性，导致肺平滑肌增殖，整个肺生长，导致梗阻和呼吸衰竭。有两种形式的
英文摘要
Lymphangioleiomyomatosis (LAM) is a rare devastating lung disease that predominantly affects young women and results in proliferation of lung smooth muscle, growth throughout the lungs leading to obstruction and respiratory failure. There are two forms of
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