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Molecular dissection of TIMP3-dependent hepatocellular carcinoma

Molecular dissection of TIMP3-dependent hepatocellular carcinoma
TIMP3依赖性肝细胞癌的分子解剖
批准号:
267783
负责人:
Khokha Rama
金额:
$45.42万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2017-09-01

项目摘要

项目成果

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中文摘要
翻译
大多数人类癌症在发展到更具侵袭性的阶段时会产生过量的金属蛋白酶活性。这些酶降解结缔组织,并从细胞表面释放关键的炎症信号。一小类抑制蛋白,称为
英文摘要
Most human cancers develop excess metalloproteinase activity as they advance to more aggressive stages. These enzymes degrade the connective tissue and shed critical inflammatory signals from the cell surface. A small family of inhibitory proteins called
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会议论文
The Terry Fox New Frontiers Program Project Grant in Mammary OMICs: Intercepting Breast Cancer Early to Improve Outcomes
Canada Research Chair - Tier 1 - CIHR Funded
  • 批准号:
    384872
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2017
  • 负责人:
    Khokha Rama
  • 依托单位:
MICROENVIRONMENT AND GENETIC DETERMINANTS IN CANCER: Discovering principles in adult tissue stem cells and cancer in breast and bone
  • 批准号:
    355177
  • 项目类别:
    Operating Grants
  • 资助金额:
    $221.31万
  • 财政年份:
    2016
  • 负责人:
    Khokha Rama
  • 依托单位:
Discovery of Novel Therapeutic Targets in Osteosarcoma
  • 批准号:
    323397
  • 项目类别:
    Operating Grants
  • 资助金额:
    $58.5万
  • 财政年份:
    2015
  • 负责人:
    Khokha Rama
  • 依托单位:
海外基金