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Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1

Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1
Rif1 强制 Sir2 在端粒、交配型基因座和 rDNA 重复序列之间维持寿命分布
批准号:
269051
负责人:
Salvi Jayesh S
金额:
$0.07万
依托单位:
依托单位国家:
加拿大
项目类别:
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2012-12-01

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中文摘要
翻译
端粒或其相互作用因子的功能障碍与基因组不稳定和过早衰老有关。sirtuin蛋白与各种衰老过程有关,它在端粒中的功能被认为可以延长酵母和哺乳动物的寿命。如何
英文摘要
Dysfunction of telomeres or their interacting factors is linked to genome instability and premature aging. Functions of sirtuin proteins, which are linked to various aging processes, at telomeres are thought to promote lifespan in yeast and mammals. How
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会议论文
Role of PABPN1 in Pax3 alternative polyadenylation and regenerative myogenesis
  • 批准号:
    318421
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $10.93万
  • 财政年份:
    2014
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Cohibin-driven turnover of non-coding RNA regulates rDNA repeats and cellular lifespan
  • 批准号:
    247822
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $10.93万
  • 财政年份:
    2011
  • 负责人:
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  • 依托单位:
Role of perinuclear tethering of repetitive DNA sequences in lifespan determination
  • 批准号:
    200587
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
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  • 负责人:
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  • 依托单位:
海外基金