Selective Translation of HIV-1 mRNAs: Mechanism and Effect on Host Innate Immune Responses
Selective Translation of HIV-1 mRNAs: Mechanism and Effect on Host Innate Immune Responses
批准号:
281409
负责人:
Cochrane Alan W
金额:
$52.57万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-03-01 至 2018-03-01
中文摘要
进入细胞后,病毒有两个目标:最大限度地产生后代病毒粒子,同时最大限度地减少先天免疫传感器的激活,从而限制病毒复制。我们小组最近的研究表明,HIV-1抑制HO
英文摘要
Upon entry into a cell, viruses have two objectives; to maximize the production of progeny virions while minimizing the activation of innate immune sensors that will limit virus replication. Recent work by our group has demonstrated that HIV-1 inhibits ho
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会议论文
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资助金额:$61.58万
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依托单位:
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Exploring Novel Inhibitors of HIV-1 Replication
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资助金额:$33.78万
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财政年份:2010
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负责人:Cochrane Alan W
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依托单位:
海外基金