The Canadian HIV Cure Enterprise (CanCURE)
The Canadian HIV Cure Enterprise (CanCURE)
批准号:
288007
负责人:
Cohen Eric A
金额:
$624.26万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-06-01 至 2018-06-01
中文摘要
尽管抗逆转录病毒疗法(ART)在降低艾滋病毒感染者死亡率方面取得了成功,但ART并未治愈艾滋病毒/艾滋病。在抗逆转录病毒治疗期间未能根除艾滋病毒感染源于病毒在体内以多种细胞类型持续存在的能力
英文摘要
Despite the success of antiretroviral therapy (ART) in decreasing mortality for HIV-infected patients, ART has not cured HIV/AIDS. The failure to eradicate HIV infection during ART stems from the virus' ability to persist in the body, in multiple cell typ
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Canadian HIV Cure Enterprise 2.0: Targeting the interplay between myeloid cells and CD4+ T-cells for HIV cure
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批准号:404213
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项目类别:Operating Grants
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资助金额:$437.1万
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财政年份:2018
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负责人:Cohen Eric A
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依托单位:
Targeting of host antiviral and immune-modulatory factors by HIV-1 Vpu: Implications for viral pathogenesis and therapy
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批准号:342347
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项目类别:Operating Grants
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资助金额:$51.8万
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财政年份:2016
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负责人:Cohen Eric A
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依托单位:
Plasmacytoid dendritic cells in HIV infection
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批准号:366602
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2016
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负责人:Cohen Eric A
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依托单位:
Examining the role of plasmacytoid dendritic cells in the control of HIV infection using humanized mice
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批准号:350795
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项目类别:Operating Grants
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资助金额:$18.12万
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财政年份:2016
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负责人:Cohen Eric A
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依托单位:
Human immunodeficiency virus (HIV)-host interactions: from mechanisms of viral persistence to infection control
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批准号:354613
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项目类别:Operating Grants
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资助金额:$179.99万
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财政年份:2016
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负责人:Cohen Eric A
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依托单位:
Advancing Public Engagement in Canadian HIV Cure Research
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批准号:334669
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项目类别:Miscellaneous Programs
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资助金额:$1.09万
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财政年份:2015
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负责人:Cohen Eric A
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依托单位:
Deciphering the functional role of Viral protein R (Vpr) during HIV infection
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批准号:328907
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项目类别:Operating Grants
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资助金额:$30.7万
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财政年份:2015
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负责人:Cohen Eric A
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依托单位:
Deciphering the functional role of Viral protein R (Vpr) during HIV infection
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批准号:309999
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项目类别:Operating Grants
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资助金额:$0.0万
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财政年份:2014
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负责人:Cohen Eric A
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依托单位:
HIV-1 Viral protein U (Vpu) as an antagonist of Tetherin/BST2: molecular mechanisms and functional implications for viral replication and transmission
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批准号:210347
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项目类别:Operating Grants
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资助金额:$51.0万
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财政年份:2010
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负责人:Cohen Eric A
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依托单位:
Recruitment of the DDB1-CUL4-DCAF1 E3 ubiquitin ligase complex by the HIV/SIV Vpr/Vpx accessory proteins: implications for viral infection, persistence and pathogenesis
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批准号:180011
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项目类别:Operating Grants
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资助金额:$60.27万
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财政年份:2009
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负责人:Cohen Eric A
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依托单位:
海外基金