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Role of genetic polymorphisms in drug metabolizing cytochrome P450 enzymes expressed in the brain for affective disorders

Role of genetic polymorphisms in drug metabolizing cytochrome P450 enzymes expressed in the brain for affective disorders
遗传多态性在大脑中表达的情感障碍药物代谢细胞色素 P450 酶中的作用
批准号:
289309
负责人:
Tyndale Rachel F
金额:
$16.38万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-06-01 至 2016-06-01

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中文摘要
翻译
细胞色素P450(CYP450)酶是一类重要的药物代谢酶,蛋白质,有助于消除外部物质,如药物或毒素,已被摄入或吸收的有机体以及物质产生的药物或毒素。
英文摘要
Cytochrome P450 (CYP) enzymes are an important class of drug metabolising enzymes, proteins that help eliminating external substances such as drugs or toxins that have been ingested or absorbed by the organism as well substances that are produced by the o
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Do men and women differ in how pharmacogenetics optimizes smoking cessation therapy?
  • 批准号:
    365094
  • 项目类别:
    Operating Grants
  • 资助金额:
    $14.54万
  • 财政年份:
    2017
  • 负责人:
    Tyndale Rachel F
  • 依托单位:
Variation in Drug Metabolism and Response
  • 批准号:
    354574
  • 项目类别:
    Operating Grants
  • 资助金额:
    $162.02万
  • 财政年份:
    2016
  • 负责人:
    Tyndale Rachel F
  • 依托单位:
Variation in nicotine metabolism in nine clinical trials: a genomics approach to personalizing smoking cessation
  • 批准号:
    354738
  • 项目类别:
    Operating Grants
  • 资助金额:
    $54.89万
  • 财政年份:
    2016
  • 负责人:
    Tyndale Rachel F
  • 依托单位:
Canada Research Chair Tier 1
  • 批准号:
    341397
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2015
  • 负责人:
    Tyndale Rachel F
  • 依托单位:
海外基金