Modelling rumen function and subsquent nutrient utilisation

该计划是我对模拟瘤胃功能和随后的营养利用的研究的延续；这是几年来一直在积极执行的一项工作方案。计划进行6项新开发，其中3项与消化有关，3项与吸收后代谢有关：(1)扩展的瘤胃脂肪酸子模型；（ii）原生动物动力学的改进描述；（iii）扩大瘤胃和后肠的物理描述；（iv）肠壁氮代谢模型；(v)肝脏;（六）乳腺。统计荟萃分析和动态建模将用于实现每个目标。在完成这些发展之后，将以用户友好的决策支持系统的形式产生一个综合模型。这将有助于制定更有效的反刍牲畜喂养策略，并制定减少甲烷排放和氮污染的方案。

The proposed programme is a continuation of my research into modelling rumen function and subsequent nutrient utilisation; a programme of work that has been actively pursued over several years. Six new developments are planned, three of which pertain to digestion and three to post-absorptive metabolism: (i) an extended rumen fatty acid sub-model; (ii) an improved description of protozoal dynamics; (iii) an expanded physical description of the rumen and hindgut; and models of nitrogen metabolism in (iv) gut wall; (v) liver; and (vi) mammary gland. Statistical meta-analysis and dynamic modelling will be used in pursuance of each objective. Having accomplished these developments, an integrated model will be produced in the form of a user-friendly decision support system. This will allow more efficient feeding strategies for ruminant livestock and options for mitigating methane emissions and nitrogen pollution to be devised.