Probing Conformationally Excited States of Aggregation-Prone Proteins Involved in Amyotrophic Lateral Sclerosis: SOD1 and TDP-43
Probing Conformationally Excited States of Aggregation-Prone Proteins Involved in Amyotrophic Lateral Sclerosis: SOD1 and TDP-43
批准号:
319597
负责人:
Culik Robert
金额:
$9.83万
依托单位:
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-11-01 至 2017-11-01
中文摘要
蛋白质聚集是当代生物物理学研究的一个主要主题,因为有观察到,在患有几种神经退行性疾病的患者中,发现了体内天然蛋白质的寡聚体组装,例如阿尔茨海默氏症,
英文摘要
Protein aggregation is a major topic in contemporary biophysics research due to the observation that oligomeric assemblies of proteins native to the body are found in patients suffering from any of several neurodegenerative diseases, such as Alzheimer's,
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