Regulation of gas exchange and metabolism in exercise, system limits and age-related modulation

我们的研究是在人类系统层面上进行的综合生理学。我们的研究项目考察了运动中气体交换、心血管反应、肌肉血流量、肌肉微血管氧合和肌肉代谢之间的控制和相互关系。我们的“衰老”模型被用来说明这些系统的可塑性，而老年人提供了一个模型来辨别心血管控制因素、气体交换和肌肉代谢的调节以及运动反应中的限制因素。我们研究的一个主题是我们对肺氧调节时间进程的研究

Our research is in integrative physiology at the systems level in humans. Our research programme examines the control and interrelationship amongst gas exchange, cardiovascular responses, muscle blood flow, muscle microvascular oxygenation, and muscle metabolism during exercise. Our ‘ageing’ model is used to illustrate the plasticity of these systems, and older adults provide a model to discern cardiovascular control factors, regulation of gas exchange and muscle metabolism, and limiting factors in the exercise response. A theme in our research is our studies of the time course of adjustment of pulmonary O