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Evaluation of the anti-angiogenic and neuroprotective effects of the BMP antagonist COCO for the treatment of neovascular ocular pathologies.

Evaluation of the anti-angiogenic and neuroprotective effects of the BMP antagonist COCO for the treatment of neovascular ocular pathologies.
评估 BMP 拮抗剂 COCO 治疗新生血管眼部病变的抗血管生成和神经保护作用。
批准号：
343413
负责人：
Larrivee Bruno
金额：
$41.77万
依托单位：
Centre de recherche de l'Hôpital Maisonneuve-Rosemont (Montral)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2021-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=343413&lang=en
关键词：
Age-Related Macular Degeneration Anti-Angiogenic Therapies Experimental Models Of Eye Disease Mechanisms Of Angiogenesis Neuroprotection Retinopathy Of Prematurity Vascular Development

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中文摘要
翻译
多种眼部疾病，如年龄相关性黄斑变性（AMD）和早产儿视网膜病变（ROP），其特征在于异常血管的过度生长。目前对这些疾病的治疗包括靶向gr的药物
英文摘要
Multiple diseases of the eye, such as age-related macular degeneration (AMD) and retinopathy of prematurity (ROP), are characterized by the excessive growth of abnormal blood vessels. Current treatments for these conditions include agents targeting the gr
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会议论文
Role of COCO/Dand5 in visual function and assessment of its therapeutic potential for ocular pathologies.
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