HoliCOW - A holobiont strategy to uncover the core microbiome in cows

人口增长正在推动食用牛产量的增加，这就需要可持续的做法，在优化动物营养的同时减少甲烷（一种重要的温室气体）的排放。该项目旨在揭示和利用奶牛全息图中的生物联系，这与奶牛吃的饲料、它们的身体功能和瘤胃中的微生物有关。该项目将利用来自奶牛全息仪的多层分子数据来识别、表征并最终控制导致动物甲烷产生的核心瘤胃微生物群。其结果将是促进基于微生物组的干预措施的新知识，这些干预措施有利于动物生产并减少其碳足迹。

Human population growth is driving a rise in cattle production for food, which necessitates sustainable practices that simultaneously optimise animal nutrition while reducing methane emissions, a critical greenhouse gas. This project aims to unravel and exploit biological connections across the cow holobiont, which pertains to the feed cows eat, their bodily function and the microbes in their rumen. This project will leverage multi-layered molecular data derived from the cow holobiont to identify, characterise and ultimately control the core rumen microbiome that causes methane production in animals. The outcome will be new knowledge to facilitate microbiome-based interventions that benefit animal production and reduce its carbon footprint.