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PCSK9 as a Cholesterolemia-Regulating Gene: Identification and Characterization of Genetic Polymorphisms in Shanghai and Ontario Chinese Populations

PCSK9 as a Cholesterolemia-Regulating Gene: Identification and Characterization of Genetic Polymorphisms in Shanghai and Ontario Chinese Populations
PCSK9 作为胆固醇血症调节基因：上海和安大略省中国人群遗传多态性的鉴定和表征
批准号：
182658
负责人：
Mbikay Majambu
金额：
$10.93万
依托单位：
Ottawa Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-03-01 至 2012-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=182658&lang=en
关键词：
Cardiovascular Disease Coronary Heart Disease Genetic Polymorphisms Genotyping Hypercholesterolemia Hypocholesterolemia Low-Density Lipoprotein Receptor Pcsk9 Pulse-Chase Analysis Receptor Binding Assay Transfection

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中文摘要
翻译
PCSK9是一种由肝脏释放到血液中的蛋白质。它的功能是限制肝细胞对血液胆固醇的吸收。这种蛋白质有许多由其基因突变引起的遗传性改变：一些罕见的形式限制了胆固醇
英文摘要
PCSK9 is a protein released into blood by the liver. Its function is to limit the uptake of blood cholesterol by liver cells. There are many heritably altered forms of this protein caused by mutations in its gene: some rare forms restrict the cholesterol
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