The Role of Aha1p in the Hsp90 Chaperone Cycle
The Role of Aha1p in the Hsp90 Chaperone Cycle
批准号:
179277
负责人:
LaPointe Paul G
金额:
$38.17万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-03-01 至 2014-03-01
中文摘要
热休克蛋白90(Hsp90)是一种分子伴侣,在癌症的发生发展中起着核心作用。发生在癌细胞中的许多调节变化是由Hsp90介导的,药物对Hsp90的抑制已经被发现。
英文摘要
The heat shock protein 90 (Hsp90) is a molecular chaperone that plays a central role in the development and progression of cancer. Many of the regulatory changes that occur in cancer cells are mediated by Hsp90 and inhibition of Hsp90 by drugs has been d
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会议论文
Investigating the regulation of the Hsp90 functional cycle by ATP, co-chaperones, and post-translational modifications
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批准号:444961
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项目类别:Operating Grants
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资助金额:$76.35万
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财政年份:2021
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负责人:LaPointe Paul G
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依托单位:
海外基金