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Elucidating novel mechanisms of extracellular nucleic acid recognition, internalization, trafficking and signaling: implications for infection, inflammation and autoimmunity.

Elucidating novel mechanisms of extracellular nucleic acid recognition, internalization, trafficking and signaling: implications for infection, inflammation and autoimmunity.
阐明细胞外核酸识别、内化、运输和信号传导的新机制:对感染、炎症和自身免疫的影响。
批准号:
368171
负责人:
Mossman Karen L
金额:
$54.34万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

项目摘要

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中文摘要
翻译
来自受感染或受损细胞的胞外或循环核酸可以是病毒或自身来源的。一旦被健康细胞识别和摄取,这些核酸就会迅速而有效地导致细胞因子的产生,包括Interf
英文摘要
Extracellular or circulating nucleic acids derived from infected or damaged cells can be of virus or self origin. Once recognized and taken up by healthy cells, these nucleic acids rapidly and potently lead to the production of cytokines, including interf
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EDI Stipend
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海外基金