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Mechanoregulation of lymphatic pumping – A coordinated contribution of ion channels, intracellular Ca2+ and protein kinase C

Mechanoregulation of lymphatic pumping – A coordinated contribution of ion channels, intracellular Ca2+ and protein kinase C
淋巴泵的机械调节 – 离子通道、细胞内 Ca2 和蛋白激酶 C 的协调作用
批准号:
RGPIN-2016-04563
负责人:
vonderWeid, PierreYves
金额:
$2.26万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
翻译
淋巴管形成一个单向运输系统,这是维持组织液和蛋白质平衡的关键,并且由于淋巴流经淋巴结,在建立适当的免疫反应中起着关键作用。在淋巴管壁开始的阶段性和节律性收缩促进淋巴液流动。这种淋巴泵送受到跨壁压力变化的关键调节。
英文摘要
Lymphatic vessels form a one-way transport system, which is key in maintaining tissue fluid and protein balances and, because lymph flows through lymph nodes, in mounting approriate immune responses. Phasic and rhythmical contractions initiated in the wall of the lymphatic vessels promote lymph flow. This lymphatic pumping is critically regulated by changes in transmural pressure.
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Mechanoregulation of lymphatic pumping - A coordinated contribution of ion channels, intracellular Ca2+ and protein kinase C
  • 批准号:
    RGPIN-2016-04563
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.52万
  • 财政年份:
    2021
  • 负责人:
    vonderWeid, PierreYves
  • 依托单位:
Mechanoregulation of lymphatic pumping - A coordinated contribution of ion channels, intracellular Ca2+ and protein kinase C
  • 批准号:
    RGPIN-2016-04563
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.26万
  • 财政年份:
    2018
  • 负责人:
    vonderWeid, PierreYves
  • 依托单位:
Mechanoregulation of lymphatic pumping – A coordinated contribution of ion channels, intracellular Ca2+ and protein kinase C
  • 批准号:
    RGPIN-2016-04563
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.26万
  • 财政年份:
    2016
  • 负责人:
    vonderWeid, PierreYves
  • 依托单位:
海外基金