Design principles for advanced new low-dose photon-counting x-ray detectors for medical radiography

自1895年伦琴发现X射线以来，X射线成像方法已经发展了100多年，现代医学对基于X射线的诊断性X射线照相术的完全依赖继续推动研究，以提高成本，有效性，安全性以及筛查和早期诊断的潜力。然而，已知与辐射有关的风险，据估计，所有癌症死亡中有200人中有1人可归因于诊断X射线成像。这种以更少的辐射产生更好的图像的迫切需要是该提议的驱动动机。

X-ray imaging methods have been under development for over 100 years since the discovery of x rays by Röntgen in 1895, and the complete dependency of modern medicine on x-ray-based diagnostic radiography continues to motivate research to improve costs, efficacy, safety and the potential for screening and early diagnoses. However, there are known risks associated with exposure to radiation and it has been estimated that 1 in 200 of all cancer deaths can be attributed to diagnostic x-ray imaging. This critical need to produce better images with less radiation is the driving motivation for this proposal.