Improving accuracy in multi-pinhole single-photon emission computed tomography

单光子发射计算机断层扫描（SPECT）是一种临床前和临床上常用的成像方式。它提供了从小鼠到人类的各种物种中活体器官功能的系列非破坏性3D成像。临床前SPECT提高了小动物研究的效率，并用于提高我们对疾病的理解，并开发新的诊断测试和治疗方法。然而，对于这些类型的研究，成像数据必须非常准确和可重复。

Single-photon emission computed tomography (SPECT) is an imaging modality that is commonly used both pre-clinically and clinically. It provides serial non-destructive 3D imaging of organ function in living subjects in a wide range of species from mouse to human. Pre-clinical SPECT increases the efficiency of small-animal research and is used to improve our understanding of disease and to develop new diagnostic tests and treatments. However, for these types of studies, it is essential that the imaging data be very accurate and reproducible.