A multi-phase clinical trial to establish biological proof-of-concept, determine safety and maximum tolerated dose, and assess efficacy of neoadjuvant ketoconazole and posaconazole in patients with recurrent high grade gliomas
A multi-phase clinical trial to establish biological proof-of-concept, determine safety and maximum tolerated dose, and assess efficacy of neoadjuvant ketoconazole and posaconazole in patients with recurrent high grade gliomas
一项多阶段临床试验，旨在建立生物学概念验证，确定安全性和最大耐受剂量，并评估酮康唑和泊沙康唑新辅助治疗复发性高级别胶质瘤患者的疗效
批准号：
377221
负责人：
Mansouri Alireza
金额：
$16.03万
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-11-01 至 2021-11-01
中文摘要
翻译
高级别胶质瘤是最常见和最具侵袭性的脑肿瘤。在许多侵袭性特征中，它们侵入大脑的距离比我们用核磁共振或显微镜看到的要远得多，因此外科医生永远不能切除整个肿瘤。这就是为什么ra
英文摘要
High grade gliomas (HGGs) are the most common and aggressive brain tumors. Among many aggressive features, they invade much farther into the brain than we can see with MRI or the microscope and so surgeons can never remove the entire tumor. That is why ra
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