Lysosomal dysfunction in smooth muscle cells relative to macrophages provides new insights into foam cell lipid accumulation
Lysosomal dysfunction in smooth muscle cells relative to macrophages provides new insights into foam cell lipid accumulation
批准号:
383114
负责人:
Dubland Joshua
金额:
$0.07万
依托单位国家:
加拿大
项目类别:
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-02-01 至 2019-02-01
关键词:
中文摘要
溶酶体是低密度脂蛋白胆固醇代谢的核心,在动脉粥样硬化中泡沫细胞的产生和动脉病变中去除多余的脂质中发挥重要作用。我们之前已经发现平滑肌细胞(SMCs)制造
英文摘要
Lysosomes are central to the metabolism of LDL-cholesterol and play an important role in both generation of foam cells in atherosclerosis and the removal of excess lipids from arterial lesions. We have previously found that smooth muscle cells (SMCs) make
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