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Bio-Sensing Textiles - Biopolymeric Protein Materials Development

Bio-Sensing Textiles - Biopolymeric Protein Materials Development
生物传感纺织品-生物聚合蛋白材料开发
批准号:
530846-2018
负责人:
DorvalCourchesne, NoémieManuelle
金额:
$1.82万
依托单位:
依托单位国家:
加拿大
项目类别:
Engage Grants Program
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-01-01 至 2019-12-31

项目摘要

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中文摘要
翻译
可穿戴技术是物联网(IOT)的关键部分,由于其在医疗保健,运动服装和电子等各个领域的应用,物联网正在迅速发展。可穿戴系统中使用的材料和组件 ** 需要具有环境和机械稳定性和灵活性 **,并与纺织工业过程兼容。Myant Technologies Inc.正在寻求pH/葡萄糖/乳酸盐湿度传感器的制造解决方案,这些传感器是环保的,稳定的,并且可以通过丝网/喷墨/ 3D打印等技术进行打印。蛋白质生物聚合物可用于组装功能化、生物相容性和生物可降解的材料,这些材料在表面工程、涂层和可穿戴技术中具有多种应用。非致病性E.大肠杆菌是一种功能性蛋白质生物聚合物,可以自组装并形成具有纳米级孔的高表面积网络。它们是非常通用的,可扩展的,并且对基因工程具有耐受性,因此,如果转化为 ** 薄膜,凝胶或涂层,它们将保持其功能。在该项目中,首次提出了大规模打印基因工程蛋白质生物聚合物。自组装蛋白质将从细菌细胞中分泌出来,并通过结合蛋白/酶结构域的融合进行工程改造,以获得所需的传感特性。经过净化处理后,它们可以以薄膜或涂层的形式应用于纺织品上,具有传感或导电等功能特性。将研究和修改所产生的 ** 生物聚合物的粘度,以产生可打印的材料。由于材料和设备是在实验室中开发的,因此开发结构的大规模生产将使用Myant Technologies Inc.提供的机器和工具进行研究。
英文摘要
Wearable technologies are key part of the internet of things (IOT) which is rapidly growing due to its**applications in various fields including healthcare, sportwear, and electronics. The materials and components**that are employed in the wearable systems require to be environmentally and mechanically stable and flexible**as well as compatible with textile industrial processes. Myant Technologies Inc. is seeking solutions for**fabrication of pH/ glucose / lactate humidity sensors that are environmentally friendly, stable, and printable by**technologies such as screen/ inkjet/ 3D printing. Protein biopolymers can be used to assemble functionalized,**biocompatible, and biodegradable materials which have a variety of applications in surface engineering,**coatings, and wearable technologies. Curli nanofibers secreted from non-pathogenic E. coli bacteria are**functional protein biopolymers that can be self-assembled and form a high surface area network with nanoscale**pores. They are extremely versatile, scalable, and tolerant to genetic engineering hence, if transformed into**films, gels, or coatings, they will maintain their functionalities. In this project, large scale printing of**genetically engineered protein biopolymers is proposed for the first time. The self-assembling proteins will be**secreted from bacteria cells and be engineered by fusion of binding protein/enzyme domains to achieve**desirable sensing properties. After purification processes, they can be applied in the form of a film or coating**on textiles with functional properties such as sensing or conductivity. The viscosity of the produced**biopolymers will be studied and modified to produce a printable material. As the materials and devices are**developed in the lab, the large-scale production of the developed structures will be investigated employing**machines and tools available at Myant Technologies Inc.
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Directed evolution of electrically conductive phage-based materials
  • 批准号:
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Signal Amplification in Rare Cell Diagnostics
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国内基金
海外基金
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