Determining the etiologies of age-related clonal hematopoiesis (ARCH), a new biomarker of cancer and cardiovascular disease development: focus on the roles of inflammation and genetic predisposition.
Determining the etiologies of age-related clonal hematopoiesis (ARCH), a new biomarker of cancer and cardiovascular disease development: focus on the roles of inflammation and genetic predisposition.
确定年龄相关克隆造血（ARCH）的病因，这是癌症和心血管疾病发展的新生物标志物：重点关注炎症和遗传易感性的作用。
批准号：
390845
负责人：
Busque Lambert
金额：
$69.66万
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-09-01 至 2023-09-01
中文摘要
翻译
衰老与血细胞基因的微小变化（突变）有关，称为年龄相关克隆造血（Age-Related Clonal Hematopoiesis， ARCH）。它看起来是良性的，因为人们的血液计数没有异常。然而，ARCH与10-有关
英文摘要
Aging is associated with the acquisition of small changes (mutations) in the genes of blood cells called Age-Related Clonal Hematopoiesis (ARCH). It seems benign as people have no abnormalities in their blood counts. However, ARCH is associated with a 10-
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会议论文
C3i - Centre for commercialization of Cancer Immunotherapy
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批准号：338079
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项目类别：Operating Grants
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资助金额：$766.02万
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财政年份：2015
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负责人：Busque Lambert
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依托单位：
Relationship between clonal architecture of aging hematopoiesis and the risk of developing age-associated myeloid cancers.
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批准号：305881
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项目类别：Operating Grants
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资助金额：$61.59万
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财政年份：2014
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负责人：Busque Lambert
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依托单位：
海外基金
