Comparison of costimulatory domains in combined GD2 chimeric antigen receptor T cell therapy and oncolytic vaccine therapy for neuroblastoma
Comparison of costimulatory domains in combined GD2 chimeric antigen receptor T cell therapy and oncolytic vaccine therapy for neuroblastoma
批准号:
406365
负责人:
Finkbeiner Melanie
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-12-01 至 2019-12-01
中文摘要
神经母细胞瘤是一种儿童癌症,在晚期或复发的疾病中预后较差。嵌合抗原受体(CAR)T细胞是治疗神经母细胞瘤的一种有前途的新疗法。在这种治疗中,被称为T细胞的免疫细胞被改造成选择性地
英文摘要
Neuroblastoma is a childhood cancer with a poor prognosis in advanced or relapsed disease. Chimeric antigen receptor (CAR) T cells is a promising new treatment for neuroblastoma. In this treatment, immune cells called T cells are engineered to selectively
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