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Deciphering the role of the Nck/PERK interaction in pancreatic beta cell function and survival

Deciphering the role of the Nck/PERK interaction in pancreatic beta cell function and survival
解读 Nck/PERK 相互作用在胰腺 β 细胞功能和存活中的作用
批准号：
408078
负责人：
Estall Jennifer
金额：
$56.57万
依托单位：
Institut de recherches cliniques de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-09-01 至 2024-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=408078&lang=en
关键词：
Cell Survival Diabetes Insulin Ipsc Islet Transplantation Islets Nck Pancreatic Beta Cells Perk Unfolded Protein Response

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中文摘要
翻译
胰腺细胞制造并释放胰岛素，一种控制人体血糖的激素。当人们患上糖尿病时，可能是因为他们的β细胞产生的胰岛素较少或没有，或者可能是细胞在试图产生胰岛素后死亡
英文摘要
Pancreatic beta cells make and release insulin, the hormone controlling blood glucose in humans. When people develop diabetes, it may be because their beta cells are producing less or no insulin, or possibly the cells have died after trying to produce too
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