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Smooth Muscle Mechanics in Airway Hyperresponsiveness and Asthma

Smooth Muscle Mechanics in Airway Hyperresponsiveness and Asthma
气道高反应性和哮喘中的平滑肌力学
批准号：
188720
负责人：
Lauzon Anne-Marie
金额：
$48.3万
依托单位：
Meakins Christie Labs (Qubec)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-09-01 至 2014-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=188720&lang=en
关键词：
Actin In Vitro Motility Assay Myosin Heavy Chain Myosin Light Chain Phosphorylation Quick Release Assay Sm22

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中文摘要
翻译
来自哮喘患者和哮喘动物模型的气道肌肉表现出缩短的速度和程度增加以及力的产生增加。关于这种增强的收缩性机制的许多假设已经形成，但h
英文摘要
Airway muscle from asthmatics and from animal models of asthma exhibits increased rate and extent of shortening as well as increased force generation. Many hypotheses on the mechanisms responsible for this enhanced contractility have been formulated but h
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CD4+T Cells, Alarmins and Human Airway Smooth Muscle Function in Asthma
Asthmatic phenotyping by microfluidic assessment of shortening velocity and contractile force of airway smooth muscle cells obtained from biopsies
Establishing the role of airway smooth muscle in human asthma and its potential as a target for therapy
Smooth Muscle Mechanics in Airway Hyperresponsiveness and Asthma
  • 批准号：
    179361
  • 项目类别：
    Operating Grants
  • 资助金额：
    $7.29万
  • 财政年份：
    2008
  • 负责人：
    Lauzon Anne-Marie
  • 依托单位：
    Meakins Christie Labs (Qubec)
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